Though all proton pump inhibitors are similar in formulation and the manner of operation, some patients experience that one works better for them as compared with others. Cost and insurance coverage are the 2 deciding factors while selecting between Prilosec and Nexium, for many patients. You may observe that one drug works better for you in comparison to the other, since every individual responds to the drugs in a different manner.
It is recommended that you consult a physician before you start the treatment with none of the drugs discussed above. The doctor will advise you the drug that works best for you. Also, there are certain moderate side effects of both drugs. These you should be aware of, before commencing the treatment.