The cause or causes of arthritis are oftentimes difficult to assess because there are a number of factors that contribute to the creation of this common disease.
Arthritis involves the distribution of cartilage. Cartilage normally protects the joint, allowing for smooth movement. Cartilage also absorbs shock when pressure is put on the joint, like when you walk. Without the usual amount of cartilage, the bones rub together, causing pain, stiffness, and swelling (inflammation).
And Even More…..
Usually affects the weight-bearing joints-the knees, hips, and facet joints (in the spine), and the finger joints.
Often, the inflammation goes away after the injury has healed, the disease is treated, or the infection has been cleared.
The inflammation doesn’t go away or destruction results in long-term pain and deformity with some injuries and diseases.
When this happens, you have chronic arthritis. Osteoarthritis is the most common type and is most likely to occur as you age.
Arthritis can occur among men and women of all ages. About 37 million people in America have arthritis of some sort. This is about 1 out of every 7 people.
Self-destructive immune response of R.A may be caused by a set of genetic susceptibility and an environmental trigger. Changing hormones may also play a significant role in disease, possibly in reply to an infection of the environment.
More than one gene has been associated with the risk of R.A. Specific genes may increase the probability that a person developing the disease, and could also partly determine how serious his condition is. However, because not all people with a genetic predisposition to rheumatoid arthritis actually have the disease, other factors should be important.
A specific environmental trigger hasn’t been found. However, some research indicates that infection by a virus or bacterium leads to rheumatoid arthritis in people genetically susceptible. That doesn’t mean that rheumatoid arthritis is contagious. People with rheumatoid arthritis seems to have more antibodies in the synovial fluid in their joints, suggesting that there may be an infection. Low levels of hormones of the adrenal gland are common in people with rheumatic arthritis. However, how hormones interact with genetic and environmental factors is unknown. Changes hormone can contribute to the progress of rheumatoid arthritis.
Rheumatoid arthritis may occur independently of other conditions. However, its causes and its relation to other diseases aren’t well understood. A different way of chronic arthritis can sometimes develop in rheumatoid arthritis. It is likewise possible that infections or other environmental triggers exist that may lead to rheumatoid arthritis in people who already have a gene for the disease.